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Jung-Hyun Shim Selected Research

2,4-bis(p-hydroxyphenyl)-2-butenal

1/2014Specificity protein 1 is a novel target of 2,4-bis (p-hydroxyphenyl)-2-butenal for the suppression of human oral squamous cell carcinoma cell growth.
1/20122,4-bis (p-hydroxyphenyl)-2-butenal (HPB242) induces apoptosis via modulating E7 expression and inhibition of PI3K/Akt pathway in SiHa human cervical cancer cells.

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Jung-Hyun Shim Research Topics

Disease

62Neoplasms (Cancer)
11/2021 - 03/2004
13Squamous Cell Carcinoma of Head and Neck
01/2019 - 10/2013
9Lung Neoplasms (Lung Cancer)
01/2021 - 05/2010
9Mouth Neoplasms (Oral Cancer)
05/2018 - 01/2010
8Colorectal Neoplasms (Colorectal Cancer)
12/2021 - 07/2009
8Esophageal Squamous Cell Carcinoma
09/2020 - 11/2019
8Malignant Mesothelioma
07/2016 - 05/2012
7Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
04/2021 - 01/2015
6Skin Neoplasms (Skin Cancer)
01/2022 - 04/2009
6Melanoma (Melanoma, Malignant)
01/2021 - 06/2015
6Carcinogenesis
05/2019 - 04/2009
5Inflammation (Inflammations)
09/2021 - 01/2015
5Neoplastic Cell Transformation
03/2017 - 01/2008
5Mesothelioma
06/2013 - 02/2012
4Squamous Cell Carcinoma (Epidermoid Carcinoma)
05/2020 - 01/2010
4Colonic Neoplasms (Colon Cancer)
08/2019 - 07/2009
4Breast Neoplasms (Breast Cancer)
12/2017 - 07/2010
4Leukemia
03/2015 - 10/2008
4Uterine Cervical Neoplasms (Cancer of the Cervix)
01/2012 - 11/2005
3Esophageal Neoplasms (Esophageal Cancer)
06/2021 - 12/2019
3Hyperuricemia
12/2018 - 06/2017
2Thymoma (Thymic Carcinoma)
09/2020 - 10/2017
2Obesity
01/2020 - 10/2008
2Neoplasm Metastasis (Metastasis)
06/2019 - 04/2016
1Alopecia (Baldness)
12/2022
1Osteosarcoma (Osteogenic Sarcoma)
01/2022
1Osteoporosis
01/2022
1Mitochondrial Diseases (Mitochondrial Disease)
11/2021

Drug/Important Bio-Agent (IBA)

30Proteins (Proteins, Gene)FDA Link
08/2019 - 07/2009
15Pharmaceutical PreparationsIBA
04/2021 - 01/2010
10AntioxidantsIBA
05/2020 - 03/2008
9Phosphotransferases (Kinase)IBA
01/2021 - 10/2008
7SurvivinIBA
01/2014 - 04/2011
6p38 Mitogen-Activated Protein KinasesIBA
12/2021 - 07/2010
6CaspasesIBA
06/2021 - 10/2008
5Gefitinib (Iressa)FDA Link
04/2021 - 10/2019
5Cyclin D1IBA
01/2014 - 05/2012
4Tyrosine Kinase InhibitorsIBA
01/2021 - 10/2019
4Protein Kinases (Protein Kinase)IBA
01/2021 - 10/2017
4licochalcone BIBA
08/2020 - 04/2016
4Annexin A5IBA
01/2020 - 12/2017
4Caspase 3 (Caspase-3)IBA
12/2019 - 04/2009
4esculetinIBA
01/2017 - 01/2015
3licochalcone HIBA
01/2022 - 01/2019
3Matrix Metalloproteinases (MMPs)IBA
11/2021 - 01/2020
3LignansIBA
11/2021 - 09/2020
3Podophyllotoxin (Condylox)FDA LinkGeneric
11/2021 - 06/2020
33-deoxysappanchalconeIBA
06/2021 - 08/2019
3deoxypodophyllotoxinIBA
04/2021 - 05/2019
3FlavonoidsIBA
01/2021 - 07/2012
3Protein Serine-Threonine Kinases (Protein-Serine-Threonine Kinase)IBA
01/2021 - 01/2020
3licochalcone CIBA
05/2020 - 12/2018
3ErbB Receptors (EGF Receptor)IBA
02/2020 - 10/2012
3Reactive Oxygen Species (Oxygen Radicals)IBA
01/2020 - 02/2012
3EnzymesIBA
12/2019 - 01/2010
3Biological ProductsIBA
12/2017 - 04/2008
3licochalcone AIBA
12/2017 - 08/2014
3Epidermal Growth Factor (EGF)IBA
01/2017 - 10/2012
3Sp1 Transcription FactorIBA
01/2017 - 10/2012
3kahweolIBA
12/2016 - 06/2012
3coumarinIBA
05/2016 - 01/2015
3beta-lapachoneIBA
02/2016 - 01/2015
3honokiolIBA
01/2015 - 06/2013
3Histones (Histone)IBA
01/2015 - 01/2008
3epigallocatechin gallate (epigallocatechin-3-gallate)IBA
09/2011 - 10/2008
3tolfenamic acidIBA
04/2011 - 07/2010
2PolyaminesIBA
09/2021 - 01/2016
2Mitogen-Activated Protein Kinase Kinases (MEKs)IBA
01/2021 - 10/2008
2Actin Depolymerizing Factors (Cofilins)IBA
01/2021 - 06/2019
2echinatinIBA
02/2020 - 11/2019
2licochalcone DIBA
01/2020 - 01/2019
2Propidium (Propidium Iodide)IBA
08/2019 - 01/2019
2DAPIIBA
01/2019 - 07/2013
2AgarIBA
01/2019 - 05/2018
2Xanthine OxidaseIBA
12/2018 - 01/2018
2Ethanol (Ethyl Alcohol)IBA
12/2018 - 01/2018
2herbacetinIBA
10/2017 - 01/2016
2Ornithine Decarboxylase (Decarboxylase, Ornithine)IBA
10/2017 - 01/2016
2DiterpenesIBA
12/2016 - 06/2012
2manumycinIBA
07/2016 - 11/2015
2jugloneIBA
06/2015 - 07/2012
2Peptidylprolyl Isomerase (Prolyl Isomerase)IBA
06/2015 - 07/2010
2QuercetinIBA
02/2015 - 10/2012
2CoffeeFDA Link
12/2014 - 06/2012
2Advanced Glycation End ProductsIBA
01/2014 - 01/2012
22,4-bis(p-hydroxyphenyl)-2-butenalIBA
01/2014 - 01/2012
2Tyrosine (L-Tyrosine)FDA Link
01/2014 - 01/2012
2FructoseIBA
01/2014 - 01/2012
2ResveratrolIBA
01/2014 - 07/2012
2Messenger RNA (mRNA)IBA
05/2012 - 03/2011
1Bimatoprost (Lumigan)FDA Link
12/2022
1Teriparatide (Parathar)FDA Link
01/2022
1Type 1 Parathyroid Hormone Receptor (Parathyroid Hormone Receptor)IBA
01/2022
1Adenylyl Cyclases (Adenylyl Cyclase)IBA
01/2022
1Adenosine Monophosphate (AMP)IBA
01/2022
1bcl-2-Associated X Protein (bcl 2 Associated X Protein)IBA
11/2021
1Cytochromes c (Cytochrome c)IBA
11/2021

Therapy/Procedure

17Therapeutics
01/2022 - 07/2009
3Immunotherapy
01/2021 - 11/2005
3Oral Administration
01/2020 - 11/2011